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KMID : 0644120120250020131
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Journal of Oriental Gynecology
2012 Volume.25 No. 2 p.131 ~ p.141
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Study of the Efficacy and Safety of "adenophorae radix extract" in the Obese Patients or Overweight
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Kim Ki-Tae
Ko Heung
Shin Seon-Mi
Kim Hyung-Jun
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Abstract
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Objectives: The purpose of this study is to evaluate the efficacy and biosafety of Adenophorae Radix(AR) extract in obesity or overweight patient.
Methods: This study is double-blind, randomized, placebo-controlled intervention Study. 30 patients with BMI 25≤ and 30> were allotted into two groups at random. In 0,6th,12th week, we had checked body weight, waist line, hip line, body fat and abdominal CT scan. In 0,12th week, we also had checked lipid metabolism and biosafety with blood test.
Results: AR treatment had a significant effect on suppressing body wight gain (p<0.01) and BMI index(p<0.01). AR treatment reduced plasma TG level but we couldn’t find statistical significance. AR treatment had produced no adverse reactions.
Conclusions: This study shows that Adenophorae Radix(AR) extract can reduce the weight, BMI. Adenophorae Radix(AR) extract can be used in obesity or overweight patient.
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KEYWORD
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Adenophorae Radix extract, obesity, overweight, Clinical trial, BMI
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